Innate Lymphoid Cell-Epithelial Cell Modules Sustain Intestinal Homeostasis
نویسندگان
چکیده
منابع مشابه
Innate lymphoid cells regulate intestinal epithelial cell glycosylation.
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Innate lymphoid cells (ILC) combine innate and adaptive immune functions and are part of the first line of defense against mucosal infections. ILC are set apart from adaptive lymphocytes by their independence on RAG genes and the resulting absence of specific antigen receptors. In this review, we will discuss the biology and function of intestinal ILC that express the nuclear hormone receptor R...
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Innate lymphoid cells (ILCs) are a key cell type that are enriched at mucosal surfaces and within tissues. Our understanding of these cells is growing rapidly. Paradoxically, these cells play a role in maintaining tissue integrity but they also function as key drivers of allergy and inflammation. We present here the most recent understanding of how genomics has provided significant insight into...
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ژورنال
عنوان ژورنال: Immunity
سال: 2020
ISSN: 1074-7613
DOI: 10.1016/j.immuni.2020.02.016